Excess mitochondrial ROS beyond redox thresholds drives oxidative damage and neurodegeneration in the retina, leading to blindness. The authors propose a unifying framework in which neurodegeneration is governed by mtROS signalling and progressive exhaustion of mitochondrial resilience.

submitted by /u/sometimeshiny [link] [comments]

• Excess mitochondrial ROS beyond redox thresholds drives oxidative damage and neurodegeneration in the retina, leading to blindness. The authors propose a unifying framework in which neurodegeneration is governed by mtROS signalling and progressive exhaustion of mitochondrial resilience.
  r/science

• Fuse raises $25M to disrupt aging loan origination systems used by U.S. credit unions 66.0%
• The kill line v Chinamaxxing: a window into how China and the US see each other 55.0%
• 'My mother cried out one last time': Palestinian boy, 12, describes how Israeli forces killed his family in car 54.0%
• Elon Musk’s xAI faces child porn lawsuit from minors Grok allegedly undressed 53.0%
• Israeli forces in southern Lebanon as ground operation announced 44.0%